Key result
The wire twisting/locking technique achieved 100% procedural success with no vascular or pulmonary complications in 18 PDA stenting procedures among 11 neonates with ductal-dependent pulmonary blood flow.
Why the study?
Patent ductus arteriosus stenting is technically challenging and prone to complications, leading researchers to evaluate the wire twisting/locking technique to improve precision and safety.
Does the wire twisting/locking technique improve procedural success and safety during PDA stenting in neonates with ductal-dependent pulmonary blood flow?
Observational (n=11)
No
Does the wire twisting/locking technique improve procedural success and safety during PDA stenting in neonates with ductal-dependent pulmonary blood flow?
The wire twisting/locking technique for PDA stenting in neonates is feasible and safe, achieving 100% procedural success without vascular or pulmonary complications in a small cohort.
Supports feasibility of wire twisting/locking for neonatal PDA stenting; leaves open need for larger comparative trials before wider adoption.
Patent ductus arteriosus (PDA) stenting is an established alternative to systemic-to-pulmonary artery shunts for neonates with ductal-dependent pulmonary blood flow, offering a less invasive approach. However, the procedure remains technically challenging and prone to complications. We evaluated the wire twisting/locking technique to improve precision and safety during PDA stenting. This retrospective study, approved by the UC San Diego Institutional Review Board, analyzed the application of the wire twisting/locking technique for PDA stenting between Jan 2021 and Dec 2024. Data were extracted from electronic medical records, including patient demographics, diagnoses, procedural details, and outcomes. The wire twisting/locking technique was applied in 18 PDA stenting procedures performed on 11 patients with complex cyanotic congenital heart disease. The procedures included initial PDA stenting ( n = 10) and PDA stent re-interventions ( n = 8), comprising four balloon dilations and four stent placements. The median age of initial stent replacement was 9 days (IQR: 8–90), and the median weight was 3.88 kg (IQR: 3.17–6.05). Access sites included carotid ( n = 10), femoral ( n = 4), axillary ( n = 2), and umbilical arteries (n = 2). The median stent diameter was 2.05 mm (IQR: 1.5–2.4), and the median stent length was 24.35 mm (IQR: 22–30 mm). The median procedure time was 91 min (IQR: 62–130) and a median radiation dose of 154.73 Gycm 2 . All procedures were successful, with no vascular or pulmonary complications. Median discharge oxygen saturation was 85% (IQR: 82–89). The wire twisting/locking technique represents a promising modification for PDA stenting. Utilizing a dynamic soft wire and opting for a single long stent simplifies stent placement and minimizes procedural complications.
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Hesari et al. (2025) conducted an observational in Complex cyanotic congenital heart disease with ductal-dependent pulmonary blood flow (n=11). Wire twisting/locking technique for PDA stenting was evaluated on Procedural success and complications. The wire twisting/locking technique achieved 100% procedural success with no vascular or pulmonary complications in 18 PDA stenting procedures among 11 neonates with ductal-dependent pulmonary blood flow.
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