Key result
Neuraxial anesthesia was associated with a 17.1% lower hospital length of stay compared to general anesthesia (mean 6.2 vs 7.4 days, IRR 0.83) in patients undergoing hip fracture surgery.
Why the study?
Although regional anesthesia may improve outcomes in hip fracture surgery, evidence for neuraxial anesthesia has been inconsistent, and it was unclear whether evolving data have influenced clinical practice.
Does regional anesthesia reduce hospital length of stay in patients undergoing hip fracture surgery?
Observational (n=620)
No
Does regional anesthesia reduce hospital length of stay in patients undergoing hip fracture surgery?
Relative Risk: 0.83 (95% CI 0.72–0.95)
Absolute Event Rate: 6.2% vs 7.4%
p-value: p=0.006
Neuraxial anesthesia is associated with a significantly shorter hospital length of stay compared to general anesthesia in patients undergoing hip fracture surgery.
Does not yet support changing anesthesia type in hip fracture surgery; leaves open whether neuraxial anesthesia shortens stay pending RCTs.
INTRODUCTION: Hip fractures are associated with significant morbidity and mortality in the United States. Over the past decade, considerable research has been directed toward identifying the optimal anesthetic and analgesic techniques for hip fracture surgery. It was hypothesized that regional anesthesia (neuraxial anesthesia and peripheral nerve blocks) may improve outcomes by avoiding the risks of general anesthesia and providing opioid-sparing analgesia in these complex patients. For neuraxial anesthesia, evidence of clinical benefit has been inconsistent in the literature; however, studies on peripheral nerve block analgesia have shown more consistent advantages. It is unclear if this data has influenced changes in clinical practice. MATERIALS AND METHODS: We conducted a retrospective single-center study of patients who underwent hip fracture surgery at the University of Virginia Medical Center from 2018 to 2022. Descriptive statistics were produced for patient demographics and clinical characteristics, and generalized linear regression models were used to examine trends in anesthetic techniques (general versus neuraxial anesthesia and use of peripheral nerve blocks) over time. We also examined the association between regional anesthesia and patient outcomes, including hospital length of stay (primary outcome), postoperative pain scores, incidence of acute kidney injury and myocardial injury, and discharge disposition (secondary outcomes), as well as diurnal variation in regional anesthesia utilization. RESULTS: We observed a 30% increase in the number of neuraxial anesthesia cases per year (from 10% (n = 12) of patients in 2018 to 33% (n = 40) in 2022), as well as an increase in peripheral nerve block utilization over time (1.7% (n = 2) of patients in 2018 to 28.1% (n = 34) in 2022). Neuraxial anesthesia was associated with a 17.1% lower hospital length of stay compared to general anesthesia (primary outcome, mean 6.2 vs 7.4 days, p = 0.006). There were no other differences in postoperative outcomes, and there was no evidence of diurnal variation in regional anesthesia utilization. CONCLUSIONS: The increase in peripheral nerve block utilization demonstrates continued progress in quality of care, while emphasizing that there is still significant room for improvement. A larger multicenter database study will be helpful to assess if the evolving literature has influenced broader changes in clinical practice.
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Kukielski et al. (2025) conducted an observational in Hip fracture (n=620). Neuraxial anesthesia vs. General anesthesia was evaluated on Hospital length of stay (IRR 0.83, 95% CI 0.72-0.95, p=0.006). Neuraxial anesthesia was associated with a 17.1% lower hospital length of stay compared to general anesthesia (mean 6.2 vs 7.4 days, IRR 0.83) in patients undergoing hip fracture surgery.
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