Key result
Patients with an atrial septal defect had a higher overall prevalence of migraine before closure compared to the general Japanese population (24.2% vs. 9.4%).
Why the study?
What is the prevalence of migraine in adult patients with atrial septal defect?
Cross-Sectional (n=95)
No
What is the prevalence of migraine in adult patients with atrial septal defect?
Absolute Event Rate: 24.2% vs 9.4%
Adult patients with atrial septal defect have a higher prevalence of migraine compared to the general population, particularly young females experiencing migraine with aura.
May prompt migraine evaluation in ASD; leaves open causal link and closure effects.
BACKGROUND: Patients with a patent foramen ovale have a high prevalence of migraine with aura (MA). However, whether patients with an atrial septal defect (ASD) have a high prevalence of migraine remains unclear. The present study aimed to determine the prevalence of migraine and its clinical characteristics in patients with ASD. FINDINGS: Ninety-five patients (age ≥ 20 years) who had undergone percutaneous ASD closure responded to a questionnaire used by neurologists to diagnose migraine either with or without aura. We diagnosed migraine before ASD closure according to the criteria of the International Headache Society. The overall prevalence of migraine seemed to be higher in the present study than in the Japanese general population (24.2% vs. 9.4%, respectively). All patients with MA were female and significantly younger than those without migraine (p < 0.01). CONCLUSIONS: Our findings suggested that the susceptibility to the development of MA differs according to sex and age in patients with cardiac shunt.
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Kato et al. (2013) conducted a cross-sectional in Atrial septal defect (n=95). Atrial septal defect vs. Japanese general population was evaluated on Overall prevalence of migraine (95% CI 16.7-33.7). Patients with an atrial septal defect had a higher overall prevalence of migraine before closure compared to the general Japanese population (24.2% vs. 9.4%).
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