Key result
Transcranial Doppler identifies ischemia risk more accurately than cerebral oximetry, avoiding ~17% unnecessary shunts.
Why the study?
Does transcranial Doppler ultrasonography provide better accuracy than cerebral oximetry for indicating selective shunting in patients undergoing carotid endarterectomy?
Observational (n=59)
Does transcranial Doppler ultrasonography provide better accuracy than cerebral oximetry for indicating selective shunting in patients undergoing carotid endarterectomy?
Effect estimate: R2 = 0.40
p-value: p=0.003
Transcranial Doppler ultrasonography is more accurate than cerebral oximetry for identifying the need for selective shunting during carotid endarterectomy, as oximetry alone has low specificity.
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TCD may reduce unnecessary shunting versus oximetry in carotid endarterectomy; leaves open whether adoption improves outcomes in prospective trials.
Grubhofer et al. (2000) conducted an observational in Carotid endarterectomy (n=59). Transcranial Doppler ultrasonography vs. Cerebral oximetry (RSO2) was evaluated on Correlation between relative decrease in middle cerebral artery velocity (%Vm,mca) and change in cerebral oximetry (DeltaRSO2) (R2 = 0.40, p=0.003). Transcranial Doppler ultrasonography identified patients at risk for ischemia more accurately than cerebral oximetry, which had a 17% false positive rate for unnecessary shunting.
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