Key result
A relative decrease of rSO2 > 20% after carotid occlusion has a high negative predictive value for cerebral ischemia, but a low positive predictive value.
Why the study?
Does regional cerebral oxygen saturation monitoring (NIRS-rSO2) accurately detect cerebral ischemia in patients undergoing carotid endarterectomy?
Does regional cerebral oxygen saturation monitoring (NIRS-rSO2) accurately detect cerebral ischemia in patients undergoing carotid endarterectomy?
NIRS-rSO2 monitoring during carotid endarterectomy is a useful non-invasive tool for predicting cerebral ischemia, though a >20% decrease has a low positive predictive value and should be used primarily to optimize cardiovascular status rather than as an absolute indication for shunting.
NIRS-rSO2 drop >20% should not trigger shunting; leaves open prospective validation of combined thresholds in carotid endarterectomy.
(Cerebral oximetry and carotid surgery) During carotid endarterectomy and carotid artery cross-clamping, various methods for monitoring of cerebral perfusion and function are suggested, including electroencephalography, measurement of the stump pressure, transcranial Doppler, somatosensory evoked potentials, regional cerebral oxygen saturation monitoring (NIRS-rSO2) or direct neurological monitoring of the awake patient during carotid cross-clamping. NIRS is a non-invasive monitoring method that may provide useful information on the most appropriate management during the procedure and postoperative recovery period in carotid endarterectomy patients. It is not possible to specify an absolute rSO2 reading as the critical value below which cerebral ischemia may develop. A relative decrease of rSO2 > 20% after carotid occlusion has an elevated negative predictive value - if rSO2 does not decrease, ischemia is unlikely, but a low positive predictive value - a decrease in rSO2 may not always indicate cerebral ischemia.
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Dragana Unic‐Stojanovic (2018) conducted a review in Carotid artery disease requiring carotid endarterectomy. Near-infrared spectroscopy (NIRS) / Cerebral oximetry was evaluated. A relative decrease of rSO2 > 20% after carotid occlusion has a high negative predictive value for cerebral ischemia, but a low positive predictive value.
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