Key result
Betamimetic drugs ritodrine and terbutaline are linked to fatal noncardiogenic pulmonary edema.
Case Report (n=7)
Betamimetic drugs such as ritodrine and terbutaline can induce potentially fatal noncardiogenic pulmonary edema.
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Betamimetics may induce fatal noncardiogenic pulmonary edema in pregnancy; case series leaves open prospective confirmation of incidence and causality.
We present six cases of pulmonary edema related to betamimetic (beta sympathomimetic amine) agents (three to ritodrine and three to terbutaline). The hemodynamic data from three patients suggest that this may be a form of noncardiogenic pulmonary edema. A seventh case, resulting in a maternal death, is included because of the association with ritodrine therapy and the instructive complications of invasive monitoring. We also propose an outline for the management of betamimetic-drug-induced pulmonary edema.
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Mabie et al. (1983) conducted a case report in Pulmonary edema (n=7). Betamimetic drugs (ritodrine and terbutaline) was evaluated on Pulmonary edema. Betamimetic drugs, specifically ritodrine and terbutaline, were associated with seven cases of pulmonary edema, including one maternal death, suggesting a noncardiogenic etiology.
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