Key result
Nicardipine combined with betamethasone for tocolysis triggers severe pulmonary edema in pregnancy.
Why the study?
There were no previous reports in the anesthesia literature of serious side effects associated with nicardipine used for tocolysis.
Does nicardipine therapy for tocolysis induce pulmonary edema in pregnant patients with preterm labor?
Case Report (n=1)
No
Does nicardipine therapy for tocolysis induce pulmonary edema in pregnant patients with preterm labor?
Nicardipine used for tocolysis in combination with betamethasone can induce pulmonary edema in pregnant patients.
Answers are grounded in this paper and cite their sources.
May signal pulmonary edema risk with nicardipine-betamethasone tocolysis; single case leaves open causality and need for safety studies.
In Brief Nicardipine is used in the treatment of premature labor. There are no previous reports in the anesthesia literature of serious side effects associated with this drug. We report a case of pulmonary edema induced by nicardipine therapy for tocolysis in a pregnant 27-yr-old patient admitted to our hospital for preterm labor with intact membranes at 27 wk of gestation. IMPLICATIONS: This report describes pulmonary edema that occurred during tocolysis with nicardipine plus betamethasone.
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Bal et al. (2004) conducted a case report in Preterm labor (n=1). Nicardipine plus betamethasone was evaluated on Pulmonary edema. Nicardipine plus betamethasone therapy for tocolysis induced pulmonary edema in a 27-year-old pregnant patient with preterm labor.
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