Key result
Tocolysis with nicardipine in a pregnant woman at 28 weeks of gestation resulted in acute pulmonary edema and respiratory failure two days after administration, which resolved with oxygen and diuresis.
Case Report (n=1)
Nicardipine used for tocolysis can cause acute pulmonary edema, requiring prompt diagnosis and management with oxygen and diuresis.
May cause delayed pulmonary edema with nicardipine tocolysis; leaves open incidence and risk factors in pregnancy.
In preterm labor, tocolytics are used to stop uterine contractions and to allow the administration of corticosteroids for fetal lung maturation, nicardipine is a calcium channel blocker increasingly used for this indication. Several adverse effects have been reported during tocolysis using nicardipine, one of the most serious complications is Acute Pulmonary Edema. We report a case of a parturient who has admitted at 28 weeks of pregnancy for preterm labor and developed a respiratory failure two days following tocolysis with nicardipine. Echocardiography and Computed Tomography Pulmonary Angiography (CTPA) ruled out a pulmonary embolism and a decompensated heart disease. The patient received oxygen therapy and diuresis for Acute Pulmonary Edema with favorable outcomes.The purpose of this paper is to discuss the risk factors for the occurrence of pulmonary edema after tocolysis, the importance of the etiologic investigation to exclude differential diagnoses and therapeutic options for management of this complication.
No takes yet. Share an insight, caveat, or question.
Motiaa et al. (2018) conducted a case report in Preterm labor (n=1). Nicardipine was evaluated on Acute Pulmonary Edema. Tocolysis with nicardipine in a pregnant woman at 28 weeks of gestation resulted in acute pulmonary edema and respiratory failure two days after administration, which resolved with oxygen and diuresis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: