Key result
Patient-specific 3D electromechanical model successfully simulates VT in ischemic cardiomyopathy to classify hemodynamic instability.
Population
A patient-specific left ventricle with ischemic cardiomyopathy
Comparison
Electrophysiology model vs electromechanics model across different circulation model scenarios
Design
Computational simulation study
Authors
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Patient-specific modeling may aid noninvasive VT stability assessment in ischemic cardiomyopathy; hypothesis-generating and requires prospective validation.
A novel patient-specific computational model combining electrophysiology, mechanics, and hemodynamics can simulate ventricular tachycardia and assess its hemodynamic stability in ischemic cardiomyopathy.
Salvador et al. (2021) studied Ischemic cardiomyopathy (n=1). 3D electromechanical computational modeling was evaluated on Hemodynamic stability and electromechanical feedback during ventricular tachycardia. A novel patient-specific 3D electromechanical model successfully simulated ventricular tachycardia in a left ventricle with ischemic cardiomyopathy, allowing classification of the arrhythmia as hemodynamically unstable.
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