Key result
Premature low-birth-weight newborns with pathological adaptation exhibit ~75% higher RMSSD than term infants.
Why the study?
The study was designed to compare autonomic circulatory regulation features in newborns across different gestational ages using heart rate variability and photoplethysmographic waveforms.
Cross-Sectional (n=50)
No
Absolute Event Rate: 26.6% vs 15.2%
p-value: p=0.005
Newborns exhibit functional immaturity of sympathetic autonomic regulation of blood circulation, with sympathetic influences prevailing in those with a pathological early neonatal adaptation period.
No takes yet. Share an insight, caveat, or question.
Higher HRV may signal sympathetic predominance in premature infants; hypothesis-generating and should not yet inform practice.
Elena N. Mureeva (2024) conducted a cross-sectional in Early neonatal adaptation (n=50). Prematurity and low birth weight (≤2500g) with pathological adaptation vs. Term birth (37-42 weeks) with physiological adaptation was evaluated on Root mean square of successive differences (RMSSD) in heart rate variability (p=0.005). Premature newborns with low birth weight and pathological adaptation exhibited significantly higher time-domain heart rate variability indices, including an RMSSD of 26.6, compared to term infants.
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