August 1, 1995Journal of Cardiovascular Electrophysiology
Postshock Sensing Performance in Transvenous Defibrillation Lead Systems: Analysis of Detection and Redetection of Ventricular Fibrillation
Key result
Ventak-Endotak delays VF redetection compared to initial detection, whereas Transvene and TVL systems are faster.
- n=93
Why the study?
Does the specific transvenous lead-pulse generator combination affect the time required for redetection of ventricular fibrillation after a failed first shock in patients with implantable defibrillators?
Population
93 patients with implantable defibrillators undergoing induced ventricular fibrillation
Comparison
Transvenous lead system-pulse generator… vs Comparison of detection versus redetection times…
Design
Cohort
Authors
Discussion
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Member takes
Implication
Device-specific VF redetection delays after failed shocks may affect ICD performance; leaves open whether pre-discharge testing improves outcomes.
Study Design
Type
Observational (n=93)
Structured PICO
Does the specific transvenous lead-pulse generator combination affect the time required for redetection of ventricular fibrillation after a failed first shock in patients with implantable defibrillators?
P
Population
93 patients with implantable defibrillators undergoing induced ventricular fibrillation to evaluate detection and redetection times across five lead-pulse generator combinations.
E
Exposure
Transvenous lead system-pulse generator combinations (Cadence-Endotak 60 series, Ventak P-Endotak 60 series, Jewel-Transvene, Cadence-TVL, and Cadence-Transvene)
C
Comparator
Comparison of detection versus redetection times within and across the different lead-pulse generator combinations
O
Outcome
Time required for detection of ventricular fibrillation and redetection after a failed first shocksurrogate
Redetection of ventricular fibrillation after a failed shock can be significantly delayed depending on the specific transvenous lead and pulse generator combination, highlighting the clinical necessity of testing redetection prior to hospital discharge.
Cite This Study
Callans et al. (1995) conducted an observational in Ventricular fibrillation (patients with implantable defibrillators) (n=93). Transvenous lead system-pulse generator combinations vs. Initial detection time (within-subject comparison) was evaluated on Difference between redetection time after a failed first shock and initial detection time of ventricular fibrillation. Redetection of ventricular fibrillation was significantly delayed compared to initial detection in the Ventak-Endotak combination (P=0.034), but shorter in Transvene and TVL systems (P<0.001).