Key result
Cardiac magnetic resonance imaging successfully diagnosed a large left atrial thrombus mimicking a myxoma in a 74-year-old woman with HHT and atrial fibrillation, leading to surgical resection.
Why the study?
Patients with hereditary hemorrhagic telangiectasia and atrial fibrillation are at high bleeding risk if anticoagulated, raising diagnostic and therapeutic dilemmas when evaluating left atrial masses.
Case Report (n=1)
Cardiac MRI is useful in differentiating left atrial thrombus from myxoma in patients with HHT and atrial fibrillation, who present unique anticoagulation challenges.
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterized by the development of arteriovenous malformations. The arteriovenous shunts may result in high output heart failure, which predisposes to atrial dilatation and atrial fibrillation. Due to recurrent bleeding from epistaxis or the gastrointestinal tract, patients with HHT and atrial fibrillation are at high risk of bleeding if anticoagulated for stroke prevention. In this report, we present a case of a 74-year-old woman with a history of HHT and atrial fibrillation who developed a large left atrial thrombus that initially was thought to represent an atrial myxoma. The diagnosis was confirmed with cardiac magnetic resonance imaging, and the patient underwent surgical resection of the thrombus. This case demonstrates the role of different imaging modalities in the assessment of left atrial masses and presents an opportunity to review the data on safety of anticoagulation in patients with HHT.
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Shahandeh et al. (2020) conducted a case report in Hereditary hemorrhagic telangiectasia and atrial fibrillation with left atrial thrombus (n=1). Cardiac magnetic resonance imaging and surgical resection was evaluated. Cardiac magnetic resonance imaging successfully diagnosed a large left atrial thrombus mimicking a myxoma in a 74-year-old woman with HHT and atrial fibrillation, leading to surgical resection.
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