Key result
Review examines how exercise training and ACE affect aortic stiffness in the elderly.
Why the study?
Does exercise training and angiotensin-converting enzyme (ACE) improve aortic stiffness in the elderly?
Does exercise training and angiotensin-converting enzyme (ACE) improve aortic stiffness in the elderly?
This review discusses the effects of exercise training and angiotensin-converting enzyme on aortic stiffness in the elderly.
Does not yet support routine use of combined exercise and ACE inhibition to reduce aortic stiffness in the elderly; leaves open the need for dedicated RCTs.
Senescence is a complex process involving many variables including genetics, lifestyle factors, and chronic diseases, the interaction of which significantly influences the manner in which we age (2). In particular, hypertension and genes of the rennin-angiotensin-aldosterone system have been associated with functional and structural changes of the large arteries, which are thought to contribute to age-related increases in the incidence of cardiovascular disease. Despite mounting evidence implicating sedentary behavior as a significant risk factor in chronic-disease morbidity and mortality among the elderly, there is a limited amount of information on the role of exercise in promoting optimal health and function in older people (27). The purpose of the present review is to discuss the effects of exercise training and angiotensin-converting enzyme (ACE) on aortic stiffness in the elderly.
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Sagiv et al. (2010) conducted a review in Aortic stiffness. Exercise training and angiotensin-converting enzyme (ACE) was evaluated on Aortic stiffness. This review discusses the effects of exercise training and angiotensin-converting enzyme on aortic stiffness in the elderly.
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