Key result
A high defibrillation threshold independently predicted an increased risk of major adverse cardiac events and death in ICD recipients (OR 4.54).
Why the study?
Does a high defibrillation threshold predict adverse clinical outcomes in ICD recipients?
Population
81 consecutive patients who received an implantable cardioverter defibrillator implantation and underwent…
Comparison
High defibrillation threshold (DFT) vs Low/normal defibrillation threshold (DFT)
Design
Cohort
Follow-up
median 432 days (range 151 to 1146 days)
Authors
Loading...
High defibrillation threshold may identify higher-risk ICD recipients; hypothesis-generating and requires prospective validation before guiding practice.
Cohort (n=81)
No
Does a high defibrillation threshold predict adverse clinical outcomes in ICD recipients?
Odds Ratio: 4.54 (95% CI 1.03–21.9)
Absolute Event Rate: 63.6% vs 21.4%
p-value: p=0.045
A high defibrillation threshold during ICD implantation is a significant predictor of major cardiac adverse events and mortality.
Enomoto et al. (2017) conducted a cohort in Implantable Cardioverter Defibrillator (ICD) recipients (n=81). High defibrillation threshold (DFT) vs. Non-high DFT was evaluated on Clinical events (major adverse cardiac events and any cause of death) (OR 4.54, 95% CI 1.03-21.9, p=0.045). A high defibrillation threshold independently predicted an increased risk of major adverse cardiac events and death in ICD recipients (OR 4.54).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: