Key result
Higher 24-hour heart rate after intracerebral hemorrhage linked to ~31% worse 90-day outcomes per 10 bpm.
Why the study?
It was unclear how heart rate and heart rate variabilities during the initial 24 hours after acute intracerebral hemorrhage contribute to worse clinical outcomes.
Cohort (n=994)
Odds Ratio: 1.31 (95% CI 1.14–1.5)
Increased mean heart rate and heart rate variability during the initial 24 hours after acute intracerebral hemorrhage are independently associated with hematoma expansion and unfavorable functional outcomes at 90 days.
No takes yet. Share an insight, caveat, or question.
May warrant closer monitoring after intracerebral hemorrhage; hypothesis-generating and should not yet change practice.
Miwa et al. (2021) conducted a cohort in Acute intracerebral hemorrhage (n=994). Increased mean heart rate and heart rate variability vs. Lower mean heart rate and heart rate variability was evaluated on Unfavorable functional outcome (modified Rankin Scale score 4 to 6 at 90 days) (aOR 1.31, 95% CI 1.14-1.50). Increased mean heart rate within 24 hours of acute intracerebral hemorrhage was associated with unfavorable functional outcome at 90 days (aOR 1.31; 95% CI 1.14-1.50 per 10 bpm increase).
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