Key result
Higher admission heart rate (≥85 vs <65 bpm) was associated with increased mortality (HR 1.50; 95% CI 1.07-2.11) and worse functional outcomes at 90 days in acute intracerebral hemorrhage.
Why the study?
Does higher admission heart rate predict mortality and poor functional outcome in patients with acute intracerebral hemorrhage?
Population
3,185 patients with acute intracerebral hemorrhage from the INTERACT 1 and 2 trials
Comparison
Higher admission heart rate vs Lowest admission heart rate (<65 bpm)
Design
Cohort
Follow-up
90 days
Authors
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Should not yet change heart rate management in acute ICH; hypothesis-generating for interventional trials.
Observational (n=3,185)
Does higher admission heart rate predict mortality and poor functional outcome in patients with acute intracerebral hemorrhage?
Hazard Ratio: 1.5 (95% CI 1.07–2.11)
p-value: p=<0.05
Higher admission heart rate is an independent predictor of mortality and poor functional outcome at 90 days in patients with acute intracerebral hemorrhage.
Qiu et al. (2016) conducted an observational in Acute intracerebral hemorrhage (n=3,185). Higher admission heart rate (≥85 bpm) vs. Lowest heart rate group (<65 bpm) was evaluated on Mortality and modified Rankin Scale score at 90 days (HR 1.50, 95% CI 1.07-2.11, p=<0.05). Higher admission heart rate (≥85 vs <65 bpm) was associated with increased mortality (HR 1.50; 95% CI 1.07-2.11) and worse functional outcomes at 90 days in acute intracerebral hemorrhage.
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