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Radicular cysts are the prevailing inflammatory jaw cysts.Historical surgical modalities, including marsupialization and enucleation, have been conventionally employed to optimise postoperative conditions and expedite the healing trajectory in the affected regions.The fundamental surgical objective is the eradication of periapical disease, instigation of bone regeneration, and facilitation of periapical tissue convalescence.Autologous platelet-rich fibrin (PRF) has emerged as a promising regenerative biomaterial with profound potential for expediting healing in oral surgical defects.PRF, a third-generation platelet concentrate, autogenously derived from patient's own blood, exhibits notable utility in root coverage applications.This case series aims to elucidate the impact of PRF on the resolution of bone defects following radicular cyst enucleation.A three-month follow-up manifested a discernible enhancement in bone density, thereby affirming the substantive efficacy of PRF in the treatment of bone defects.
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