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This article presents a case of Urrets-Zavalia Syndrome (UZS), a rare complication following an uneventful penetrating keratoplasty (PKP) carried out for macular corneal dystrophy (MCD) in a 23-year-old patient in a tertiary care hospital.The patient exhibited peripheral anterior synechiae (PAS) with elevated intraocular pressure (IOP) during his one-week follow-up.Despite the administration of topical and systemic IOP-lowering medications as well as miotic agents, the patient's IOP remained unresponsive.Consequently, we performed a therapeutic synechiolysis to alleviate the elevated IOP.Early surgical intervention proved crucial in preventing the patient from developing glaucomatous damage secondary to elevated IOP.This case highlights the significance of close monitoring with prompt surgical management to prevent sight-threatening complications associated with UZS following PKP.
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