Key result
Near-infrared imaging shows no significant benefit over subjective assessment for severe intestinal complications.
Why the study?
Adequate vascular perfusion is essential to prevent anastomotic leakage after intestinal resection, and NIR-ICG provides objective assessment, prompting evaluation of its association with outcomes in intestinal and mesenteric injuries.
Does near-infrared imaging using indocyanine green reduce postoperative complications in patients undergoing surgery for intestinal and mesenteric injuries?
Cohort (n=37)
No
Does near-infrared imaging using indocyanine green reduce postoperative complications in patients undergoing surgery for intestinal and mesenteric injuries?
Absolute Event Rate: 0% vs 30.8%
p-value: p=0.076
The use of near-infrared imaging with indocyanine green during surgery for intestinal and mesenteric injuries may reduce the risk of postoperative complications, particularly in patients undergoing intestinal resection.
May support NIR-ICG for injury perfusion assessment; hypothesis-generating for prospective trials on leak prevention.
Anastomotic leakage after intestinal resection is one of the most serious complications of surgical intervention for hollow viscus injury. Adequate vascular perfusion of the anastomotic site is essential to prevent anastomotic leakage. Near-infrared imaging using indocyanine green (NIR-ICG) is useful for the objective assessment of vascular perfusion. The aim of this study was to evaluate the association of NIR-ICG with intestinal and mesenteric injuries. This was a retrospective, single-center study of patients undergoing surgery for intestinal and mesenteric injuries. NIR-ICG was used to evaluate vascular perfusion. Postoperative complications were assessed between NIR-ICG and non-NIR-ICG groups.The use of NIR-ICG was associated with a lower incidence of Clavien-Dindo grade ≥ III complications with a statistical tendency (p = 0.076). When limited to patients that underwent intestinal resection, the use of NIR-ICG was significantly associated with a lower risk of perioperative complications (p = 0.009). The use of NIR-ICG tended to associate with the lower incidence of postoperative complications after intestinal and mesenteric trauma surgery. NIR-ICG was associated with a significantly lower risk of complications in patients undergoing intestinal resection. The NIR-ICG procedure is simple and quick and is expected to be useful for intestinal and mesenteric trauma.
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Yamaguchi et al. (2021) conducted a cohort in Intestinal and mesenteric injury (n=37). Near-infrared imaging using indocyanine green (NIR-ICG) vs. Non-NIR-ICG (subjective clinical assessment) was evaluated on Intestinal-related Clavien-Dindo grade ≥ III complications (p=0.076). The use of near-infrared imaging using indocyanine green was associated with a lower incidence of intestinal-related Clavien-Dindo grade ≥ III complications compared to subjective assessment, though this did not reach statistical significance (0% vs 30.8%, p=0.076).
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