Key result
Higher Cardiometabolic Index linked to ~2% greater all-cause and diabetes-related mortality risk per SD.
Why the study?
Cardiometabolic syndrome is a major risk factor for cardiovascular diseases and type 2 diabetes mellitus, necessitating reliable mortality risk prediction tools.
Does the Cardiometabolic Index predict all-cause and cause-specific mortality in adult patients with cardiometabolic syndrome?
Cohort (n=5,476)
Does the Cardiometabolic Index predict all-cause and cause-specific mortality in adult patients with cardiometabolic syndrome?
Hazard Ratio: 1.02
p-value: p=0.033
The Cardiometabolic Index is a significant predictor of all-cause and diabetes-related mortality, but not cardiovascular mortality, in adults with cardiometabolic syndrome.
CMI was associated with all-cause and diabetes mortality in CMS; supports risk stratification but remains hypothesis-generating pending prospective validation.
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Li et al. (2026) conducted a cohort in Cardiometabolic syndrome (n=5,476). Cardiometabolic Index (CMI) was evaluated on all-cause mortality (HR 1.02, p=0.033). Higher Cardiometabolic Index was associated with increased all-cause mortality (HR 1.02 per SD increase, P=0.033) and diabetes-related mortality in patients with cardiometabolic syndrome.
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