Role of Purkinje Fibers in the Maintenance of Ventricular Fibrillation

any experimental and clinical studies on the mechanisms of ventricular fibrillation (VF) have been performed over the past 10 decades.The underlying mechanisms of VF have been discussed from different points of view: initiation and maintenance.It is beyond question that reentry, triggered activity or automaticity initiates VF, but the mechanism of its maintenance is not fully determined.Although the duration from the onset of VF may affect its electrophysiological features, maintenance of VF has been explained by the coexistence of 2 or more unstable multiple wavelets or mother rotors. 1