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Introduction. Left atrial septal pouch (LASP) is a rare, poorly understood cause of embolic cryptogenic stroke. Along with this, there is no understanding of the role of this pathology in the development of transient global amnesia (TGA) due to possible embolism. Aim. To present a clinical case of a patient with TGA and LASP. Material and methods. This article presents a description of the clinical case of a young patient with TGA and a concomitant anomaly of the interatrial septum in the form of LASP and patent foramen ovale (PFO). In order to search for published clinical cases and reviews on the pathogenetic significance of LASP, the database of medical and biological publications PubMed was analyzed. Results. Patient O., 39-year old, with a history of migraine due to provoking factors (Valsalva maneuver), suff ered an episode of TGA. Angiography did not reveal any pathology. There were no acute infarctions according to magnetic resonance imaging. During the diagnostic search, transesophageal echocardiography revealed a combined anomaly of the interatrial septum in the form of a combination of LASP with PFO. Conclusion. LASP is a rare and little-studied anomaly of the formation of the interatrial septum. Transthoracic echocardiography is not a sensitive method for identifying this pathology. The imaging method of choice is TEE. If the presence of LASP is suspected, clinicians should be aware of the need to exclude concomitant interatrial communications using a bubble study.
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Mekhryakov et al. (2025) studied this question.
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