Sex-specific triggers for right ventricular outflow tract tachycardia
Key result
Men are ~124% more likely than women to report predictable RVOT-VT triggers like exercise or stress.
- P<.01
- n=47
Why the study?
Are there sex-specific triggers for symptomatic right ventricular outflow tract tachycardia?
Population
47 patients (34 women, 13 men) referred for ablation of right ventricular outflow tract tachycardia (RVOT-VT)
Comparison
Patient interview regarding triggers for… vs Comparison between men and women
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support sex-specific trigger assessment in RVOT-VT evaluation; observational data leaves open prospective validation before practice change.
Study Design
Type
Observational (n=47)
Structured PICO
Are there sex-specific triggers for symptomatic right ventricular outflow tract tachycardia?
P
Population
47 patients (34 women and 13 men) referred for ablation of RVOT-VT interviewed to identify sex-specific triggers.
E
Exposure
Patient interview regarding triggers for symptomatic RVOT-VT (exercise, stress, caffeine, fatigue, and hormonal flux in women)
C
Comparator
Comparison between men and women
O
Outcome
Self-reported triggers for symptomatic RVOT-VT initiationpatient reported
Main Result
Absolute Event Rate: 92% vs 41%
p-value: p=<.01
Triggers for RVOT-VT are sex-specific, with women frequently reporting hormonal flux and men more commonly reporting exercise or stress.
Cite This Study
Marchlinski et al. (2000) conducted an observational in Right ventricular outflow tract tachycardia (RVOT-VT) (n=47). Male sex vs. Female sex was evaluated on RVOT-VT predictably triggered by exercise, stress, or caffeine (p=<.01). Men were significantly more likely than women to report that their RVOT-VT was predictably triggered by exercise, stress, or caffeine (92% vs 41%, P<.01).