Key result
Dopamine infusion increases HR, cardiac index, and PA and aortic pressures while decreasing SVR.
Why the study?
Does dopamine infusion improve haemodynamic parameters in patients with pulmonary hypertension?
Does dopamine infusion improve haemodynamic parameters in patients with pulmonary hypertension?
Dopamine safely increases cardiac output without significantly increasing pulmonary vascular resistance in patients with pulmonary hypertension.
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May support dopamine for acute hemodynamic support in pulmonary hypertension without raising pulmonary vascular resistance; leaves open outcome effects.
Holloway et al. (1976) studied Pulmonary hypertension (n=21). Dopamine infusion vs. Baseline (before dopamine infusion) was evaluated on Haemodynamic measurements (heart rate, pulmonary artery mean pressure, aortic mean pressure, cardiac index, systemic vascular resistance). Dopamine infusion significantly increased heart rate, pulmonary artery mean pressure, aortic mean pressure, and cardiac index, while decreasing systemic vascular resistance in both groups.
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