Why the study?
Does intravenous dopamine elicit a different renal response in hypertensive patients compared to normotensive subjects?
Population
15 subjects (8 hypertensive patients and 7 normotensive volunteers)
Comparison
Intravenous dopamine (2 micrograms/min/kg) vs Normotensive volunteer subjects receiving the…
Design
Other
Authors
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Indicates possible dopaminergic deficit in hypertension; leaves open whether agonists have therapeutic role.
Does intravenous dopamine elicit a different renal response in hypertensive patients compared to normotensive subjects?
Hypertensive patients exhibit hyperresponsiveness to exogenous dopamine, suggesting a baseline deficit in dopaminergic activity in hypertension.
Andréjak et al. (1986) studied this question.
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