Population
48 patients with essential hypertension aged 18 to 27 years and 25 age-matched normotensive subjects.
Design
Case-control
Authors
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Association in case-control data warrants no practice change; leaves open causal role of renal catecholamine excretion in essential hypertension.
Young patients with essential hypertension exhibit increased urinary dopamine and noradrenaline excretion compared to normotensive subjects, suggesting elevated renal conversion of dopa to dopamine.
Saito et al. (1994) studied this question.
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