Why the study?
Is peripheral dopaminergic activity decreased in men with untreated essential hypertension compared to normotensive controls?
Population
76 men, including 42 with untreated, sustained essential hypertension and 34 age-matched normotensive men.
Design
Case-control
Authors
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May implicate reduced peripheral dopaminergic activity in hypertension; leaves open causality and therapeutic relevance.
Is peripheral dopaminergic activity decreased in men with untreated essential hypertension compared to normotensive controls?
Patients with essential hypertension exhibit decreased peripheral dopaminergic activity compared to normotensive individuals, suggesting a potential pathophysiological role in the condition.
Kjeldsen et al. (1983) studied this question.
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