Key result
Plasma dopamine β-hydroxylase concentration positively correlated with resting diastolic blood pressure and plasma noradrenaline amounts in a study of 28 patients.
Population
n=28 patients, 20 of whom had essential hypertension
Design
Cross-sectional
Authors
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Supports sympathetic role in essential hypertension; hypothesis-generating and should not change practice.
Observational (n=28)
The study supports the hypothesis that the sympathetic nervous system contributes to elevated blood pressure in essential hypertension by demonstrating a positive correlation between plasma dopamine β-hydroxylase, noradrenaline, and diastolic blood pressure.
Geffen et al. (1973) conducted an observational in Essential hypertension (n=28). Plasma dopamine β-hydroxylase (DβH) concentration was evaluated on Correlation with resting diastolic blood pressure and plasma noradrenaline. Plasma dopamine β-hydroxylase concentration positively correlated with resting diastolic blood pressure and plasma noradrenaline amounts in a study of 28 patients.
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