Key result
Vincristine and conventional-dose cyclophosphamide linked to AMI in a patient with no prior cardiac history.
Population
1 patient with chronic lymphocytic leukemia and no antecedent cardiac history
Design
Case_report
Authors
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May warrant cardiac monitoring during vincristine-cyclophosphamide therapy; leaves open causality and generalizability.
Case Report (n=1)
Highlights the potential for acute myocardial infarction as a serious complication of vincristine and conventional-dose cyclophosphamide therapy.
Federman et al. (1997) conducted a case report in Chronic lymphocytic leukemia (n=1). Vincristine and cyclophosphamide was evaluated on Acute myocardial infarction. Administration of vincristine and conventional doses of cyclophosphamide was associated with acute myocardial infarction in a patient with chronic lymphocytic leukemia and no prior cardiac history.
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