Key result
Vinca alkaloid chemotherapy linked to anterior MI in a young man without cardiac risk factors.
Population
32-year-old male with stage IIIA nodular sclerosing Hodgkin's disease and no cardiac risk factors (n=1)
Design
Case_report
Authors
Loading...
May warrant vigilance for spasm-mediated MI during vinca alkaloid therapy in young patients; leaves open need for prospective confirmation.
Case Report (n=1)
Vinca alkaloid-containing chemotherapy regimens can rarely induce myocardial infarction, likely via coronary artery spasm, necessitating drug discontinuation and supportive care.
House et al. (1992) conducted a case report in Hodgkin's disease and myocardial infarction (n=1). Chemotherapy containing vinca alkaloids was evaluated on Myocardial infarction. Chemotherapy containing vinca alkaloids was associated with an uncomplicated anterior wall myocardial infarction in a 32-year-old man with Hodgkin's disease and no cardiac risk factors.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: