Key result
The study aimed to generate a validated risk-assessment model to estimate the absolute risk of postpartum venous thromboembolism, though specific results were not reported in the truncated abstract.
Why the study?
Can a validated risk-assessment model accurately estimate the absolute risk of postpartum VTE to tailor thromboprophylaxis?
Can a validated risk-assessment model accurately estimate the absolute risk of postpartum VTE to tailor thromboprophylaxis?
Answers are grounded in this paper and cite their sources.
This commentary discusses the development and validation of a risk prediction model to individualize thromboprophylaxis for postpartum venous thromboembolism.
Commentary on: Sultan AA, West J, Grainge MJ, et al. Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study. BMJ 2016;355:i6253.[OpenUrl][1][Abstract/FREE Full Text][2] Around 1 in 1000 postpartum women suffers from venous thromboembolism (VTE).1 The occurrence of deep vein thromboses (DVT), often found in proximal veins, may affect long-term quality of life,2 and pulmonary embolisms (PE) are a leading cause of direct maternal death in this very healthy population. Given the overall low absolute risk of VTE, as well as the cost of thromboprophylaxis and its possible side-effects, the use of prophylactic heparin is unreasonable if given universally, but should be tailored to individual risks. The aim of this study was to generate a validated risk-assessment model or prediction tool to estimate the absolute risk of postpartum VTE in individual women. Using two population-based … [1]: {openurl}?query=rft.jtitle%253DBMJ%26rft_id%253Dinfo%253Adoi%252F10.1136%252Fbmj.i6253%26rft_id%253Dinfo%253Apmid%252F27919934%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bmj&resid=355/dec05_12/i6253&atom=%2Febmed%2F22%2F3%2F98.atom
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Blondon et al. (2017) conducted an editorial in Postpartum venous thromboembolism. Risk prediction model was evaluated on Absolute risk of postpartum VTE. The study aimed to generate a validated risk-assessment model to estimate the absolute risk of postpartum venous thromboembolism, though specific results were not reported in the truncated abstract.
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