Key result
First trimester ultrasound detects severe tricuspid valve dysplasia and pulmonary atresia in a 13-week fetus.
Case Report (n=1)
Demonstrates the feasibility of detecting severe congenital heart defects like tricuspid valve dysplasia and pulmonary valve atresia as early as the first trimester using ultrasound.
Supports potential for first-trimester detection of complex congenital heart defects; leaves open its role in routine prenatal screening.
Early diagnosis of congenital heart defect (CHD) increased in the last two decades, following technological evolution. A recent meta-analysis (Yu, 2020), on diagnostic accuracy in ultrasound detection of major CHD in the first trimester of pregnancy, reported an overall sensitivity of 75%. Ultrasound imaging of this case refers to a tricuspid valve dysplasia with right atriomegaly and pulmonary valve atresia diagnosed in a 13-week gestational-age fetus with low risk for chromosomal abnormalities. To our knowledge, this is the first case describing such features in the first trimester. We believe the precocity and severity of onset make this a case of diagnostic interest.
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Cordisco et al. (2021) conducted a case report in Tricuspid valve dysplasia with right atriomegaly and pulmonary valve atresia (n=1). First trimester ultrasound imaging was evaluated. First trimester ultrasound imaging successfully identified severe tricuspid valve dysplasia with right atriomegaly and pulmonary valve atresia in a 13-week gestational-age fetus.
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