Key result
Type V hyperlipoproteinemia in two monozygotic twin-brothers was associated with chronic relapsing pancreatitis, splenic vein thrombosis, and segmental portal hypertension, leading to death in one.
Case Report (n=2)
Early recognition of type V hyperlipoproteinemia and appropriate medical treatment may prevent unnecessary and potentially fatal surgical interventions for associated chronic relapsing pancreatitis.
Case reports of severe complications in monozygotic twins support heightened clinical suspicion; leaves open questions on optimal management and inheritance patterns.
SummaryTwo cases of type V hyperlipoproteinemia in monozygotic twin-brothers are described. Hyperlipemia was associated with recurrent attacks °f abdominal pain, bouts of chronic relapsing Pancreatitis, thrombosis of the splenic vein, splenomegaly and segmental portal hypertension.One patient died following a drainage operaion of a pancreatic abscess. Early recognition °f the disease and appropriate treatment may Prevent useless surgical intervention.A family study was undertaken and three addional case of type IV hyperlipoproteinemia were found.
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Hoste et al. (1978) conducted a case report in Type V hyperlipoproteinemia and chronic relapsing pancreatitis (n=2). Type V hyperlipoproteinemia was evaluated on Clinical presentation and outcomes (pancreatitis, thrombosis, death). Type V hyperlipoproteinemia in two monozygotic twin-brothers was associated with chronic relapsing pancreatitis, splenic vein thrombosis, and segmental portal hypertension, leading to death in one.
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