Key result
An infant presented with an atypical clinical course of Kawasaki syndrome, highlighting the need to consider this diagnosis and perform cardiac evaluation in infants with prolonged fever and rash.
Case Report (n=1)
Infants with prolonged fever and atypical rash should be evaluated for Kawasaki syndrome, including echocardiography, even if they do not meet classic CDC criteria.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for atypical Kawasaki in infants; prospective studies needed to validate expanded diagnostic criteria and cardiac evaluation.
Kawasaki syndrome (KS) is a vasculitis of childhood, the etiology of which is unknown. Diagnosis is based on the Center for Disease Control (CDC) criteria in which skin and mucous membrane findings play a key role. Coronary artery involvement can be fatal. Prompt diagnosis and initiation of therapy can reduce the risk of cardiac complication. Autopsy findings of patients with KS who did not fit CDC criteria for symptoms have been reported. Infants, in particular, may have an atypical clinical course resulting in delayed diagnosis and initiation of treatment. This case presents an infant with fever and an atypical rash who did not fit diagnostic criteria. Differential diagnosis of infants with prolonged fevers and rash, who do not fit into other diagnostic categories, should include KS and an appropriate cardiac examination including consideration of an echocardiogram.
No takes yet. Share an insight, caveat, or question.
Allan D. Friedman (1988) conducted a case report in Kawasaki syndrome (n=1). Atypical presentation of Kawasaki syndrome was evaluated. An infant presented with an atypical clinical course of Kawasaki syndrome, highlighting the need to consider this diagnosis and perform cardiac evaluation in infants with prolonged fever and rash.
Synapse has enriched 10 related papers. Consider them for comparative context: