Key result
All adult rat soleus type 2 fibers contain both fast and slow myosin light chains.
Population
Single muscle fibers isolated from soleus and extensor digitorum longus muscle of adult rats
Design
Preclinical
Authors
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Questions strict fast/slow myosin segregation in rodent fibers; leaves open translation to human cardiac or skeletal muscle.
Type 2 fibers in rat soleus muscle contain both fast and slow types of myosin light chains.
Mizusawa et al. (1982) studied this question. Skinned fiber method and gel-electrophoreses was evaluated on Myosin light chain pattern and sensitivity to strontium ions. All type 2 fibers isolated from the soleus muscle of adult rats contained both fast and slow types of myosin light chains.
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