What is the clinical evidence from this study?

Study design: Other. Population: Developing chick embryo and tissue-cultured myotubes. Intervention: Developmental stage. Primary outcome: Expression of fast and slow isoforms of the Ca2+-ATPase.

December 1, 1987Developmental BiologyOpen Access

Expression of fast and slow isoforms of the Ca2+-ATPase in developing chick skeletal muscle

View Full Paper

Ask AI

Bookmark

Key result

Developing chick muscle fibers express fast and slow Ca2+-ATPase isoforms independently of myosin heavy chain.

Authors

ZKZaven KaprielianCalifornia Institute of Technology DFDouglas M. FambroughCalifornia Institute of Technology

Discussion

Member takes

Implication

May inform avian myogenesis models but should not change clinical practice; leaves open isoform coordination in mammalian muscle.

PICO

Population

Developing chick embryo and tissue-cultured myotubes

Exposure / Comparator

Developmental stage

Primary Outcome

Expression of fast and slow isoforms of the Ca2+-ATPase

Cite This Study

Kaprielian et al. (1987) studied Developing chick embryo and tissue-cultured myotubes. Developmental stage was evaluated on Expression of fast and slow isoforms of the Ca2+-ATPase. All developing chick skeletal muscle fibers expressed both fast and slow isoforms of the Ca2+-ATPase, which are not coordinately expressed with myosin heavy chain.

synapsesocial.com/papers/6aa4147d04de40c43bb15681 https://doi.org/10.1016/0012-1606(87)90502-1

View Full Paper

Ask AI

Bookmark

Expression of fast and slow isoforms of the Ca2+-ATPase in developing chick skeletal muscle

Discussion

Member takes

Implication

PICO

Cite This Study

Expression of fast and slow isoforms of the Ca2+-ATPase in developing chick skeletal muscle

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider