Key result
Peripheral vascular calcification was significantly higher in patients with false negative results for both pulse palpation and ankle brachial index screening tests (P<0.0001).
Why the study?
Does peripheral vascular calcification increase false negative rates of pulse palpation and ankle brachial index screening for peripheral arterial occlusive disease in patients with diabetes?
Cross-Sectional (n=200)
Does peripheral vascular calcification increase false negative rates of pulse palpation and ankle brachial index screening for peripheral arterial occlusive disease in patients with diabetes?
p-value: p=<0.0001
Below-knee vascular calcification increases the rate of false negative results for ankle brachial index, making combined pulse palpation and ABI the best screening strategy for peripheral arteriopathy in diabetes.
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May explain false negatives in ABI/palpation screening for diabetic PAD; hypothesis-generating and should not yet change practice.
Aubert et al. (2013) conducted a cross-sectional in diabetes at high risk of cardiovascular disease (n=200). Peripheral vascular calcification was evaluated on False negative screening tests for peripheral arterial occlusive disease (p=<0.0001). Peripheral vascular calcification was significantly higher in patients with false negative results for both pulse palpation and ankle brachial index screening tests (P<0.0001).
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