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January 1, 1990Scandinavian Journal of Thoracic and Cardiovascular Surgery

Value of C-Reactive Protein in Detecting Complications After Open-Heart Surgery in Children

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Key result

Higher serum CRP is linked to postoperative complications in children.

  • n=206

Why the study?

Do serial measurements of CRP and body temperature detect postoperative complications in children after open-heart surgery?

Population

206 children (mean age 4.6 years) who underwent primary open-heart surgery

Design

Cohort

Follow-up

14 days

Authors

MAMerja AronenUniversity of Helsinki

Discussion

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Implication

Higher CRP may signal complications after pediatric open-heart surgery; hypothesis-generating and requires prospective validation before guiding care.

Study Design

Type

Observational (n=206)

Structured PICO

Do serial measurements of CRP and body temperature detect postoperative complications in children after open-heart surgery?

P
Population
206 children with a mean age of 4.6 years who underwent primary open-heart surgery, evaluated retrospectively for 14 days postoperatively.
E
Exposure
Serial measurements of serum C-reactive protein (CRP) and body temperature daily for 14 days postoperatively
O
Outcome
Postoperative complications

Serial measurements of CRP may serve as a useful biomarker for detecting postoperative complications in pediatric patients following open-heart surgery.

Cite This Study

Merja Aronen (1990) conducted an observational in Postoperative complications after open-heart surgery (n=206). Serum C-reactive protein (CRP) was evaluated on Postoperative complications. Serum C-reactive protein concentrations were significantly higher in children with postoperative complications (which occurred in 38% of patients) than in those with an uneventful recovery.

synapsesocial.com/papers/6aa42cfdef148610eb1aba42https://doi.org/10.3109/14017439009098058

Topics

Congenital heart disease adults
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects on C-reactive protein on the lymphoid system. I. Binding to thymus-dependent lymphocytes and alteration of their functions.1975 · 155 citations
  2. 2C‐reactive protein in patients undergoing cardiac surgery1986 · 53 citations
  3. 3Quantitation of “Acute-phase Proteins” Postoperatively: Value in Detection and Monitoring of Complications1976 · 194 citations
  4. 4C-REACTIVE PROTEIN (CRP) IN EARLY DIAGNOSIS OF NEONATAL SEPTICEMIA2008 · 126 citations
  5. 5Control of the Acute Phase Response1978 · 307 citations