Key result
High-dose IV epinephrine achieves ROSC in 2 patients with refractory cardiac arrest.
Why the study?
Does high-dose epinephrine improve return of spontaneous circulation in patients with cardiac arrest refractory to standard therapy?
Case Report (n=2)
Does high-dose epinephrine improve return of spontaneous circulation in patients with cardiac arrest refractory to standard therapy?
High-dose epinephrine may be effective in achieving return of spontaneous circulation in patients with cardiac arrest refractory to standard therapy.
No takes yet. Share an insight, caveat, or question.
High-dose epinephrine may aid ROSC in refractory arrest; hypothesis-generating and requires RCTs before any practice change.
E. M. Koscove (1988) conducted a case report in Cardiac arrest (n=2). High-dose intravenous epinephrine hydrochloride vs. Standard therapy was evaluated on Return of spontaneous circulation. High-dose intravenous epinephrine therapy resulted in the return of spontaneous circulation in two patients with cardiac arrest refractory to standard therapy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: