Key result
Laparoscopic emergency colorectal surgery resulted in a 30-day postoperative complication rate of 27% (95% CI 13-46%) compared to 42% (95% CI 25-61%) for open surgery.
Why the study?
To evaluate the feasibility, safety, and acceptability of conducting a large-scale phase III RCT comparing emergency laparoscopic versus open surgery for acute colorectal pathology.
Does laparoscopic emergency colorectal surgery improve safety compared to open surgery in patients with acute colorectal pathology?
Population
64 patients requiring emergency surgery for acute colorectal pathology across five centres
Comparison
Laparoscopic surgery vs open surgery
Design
Multicentre single-blind parallel-group pragmatic feasibility RCT
Follow-up
30 days
Authors
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May support laparoscopic feasibility in emergency colorectal surgery; leaves open definitive safety confirmation in a phase III RCT.
RCT (n=64)
Single-blind
1:1
Yes
Does laparoscopic emergency colorectal surgery improve safety compared to open surgery in patients with acute colorectal pathology?
Absolute Event Rate: 27% vs 42%
Laparoscopic emergency colorectal surgery appears feasible and may have an acceptable safety profile compared to open surgery, supporting a definitive phase III RCT.
Harji et al. (2020) conducted an RCT in Acute colorectal pathology (n=64). Laparoscopic surgery vs. Open surgery was evaluated on 30-day postoperative complication rate. Laparoscopic emergency colorectal surgery resulted in a 30-day postoperative complication rate of 27% (95% CI 13-46%) compared to 42% (95% CI 25-61%) for open surgery.