Key result
Prototype transport containers with EPIC sensors enable recording of physiological and environmental parameters in mice.
Why the study?
Laboratory mice may experience significant stress during transportation that can negatively affect experimental research results, prompting the need for monitoring physiological and environmental parameters.
A novel transportation container equipped with EPIC sensors allows for the monitoring of physiological and environmental parameters to assess stress in laboratory mice.
May enable stress monitoring during mouse transport; leaves open translation to clinical or cardiovascular models.
Laboratory mice are used in biomedical research as “models” for studying human disease. These mice may be subject to significant levels of stress during transportation that can cause alterations that could negatively affect the results of the performed investigation. Here, we present the design and realization of a prototypical transportation container for laboratory mice, which may contribute to improved laboratory animal welfare. This prototype incorporates electric potential integrated circuit (EPIC) sensors, which have been shown to allow the recording of physiological parameters (heart rate and breathing rate) and other sensors for recording environmental parameters during mouse transportation. This allows for the estimation of the stress levels suffered by mice. First experimental results for capturing physiological and environmental parameters are shown and discussed.
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González-Sánchez et al. (2019) studied Laboratory mice transportation stress. Prototypical transportation container with EPIC sensors was evaluated on Recording of physiological and environmental parameters. A prototypical transportation container incorporating electric potential integrated circuit (EPIC) sensors allowed the recording of physiological and environmental parameters in laboratory mice.
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