Key result
Commercial EPIC sensors monitor heart and breathing rates in non-restrained, non-sedated laboratory mice.
EPIC sensors demonstrate potential for non-invasive, contactless monitoring of heart and breathing rates in non-restrained laboratory mice, which could improve animal welfare monitoring.
May improve welfare monitoring in rodent models; leaves open validation in other species before broader use.
Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown.
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González-Sánchez et al. (2016) studied Laboratory mice. Electric potential integrated circuit (EPIC) sensors was evaluated on Suitability for monitoring heart rate and breathing rate. Commercially available electric potential integrated circuit (EPIC) sensors were evaluated for monitoring the heart and breathing rates of non-restrained, non-sedated laboratory mice.
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