Key result
Sleep duration shows no overall link to arterial stiffness except for long sleep in Dutch men.
Why the study?
Does short or long sleep duration increase arterial stiffness in a multi-ethnic population?
Cohort (n=10,994)
Does short or long sleep duration increase arterial stiffness in a multi-ethnic population?
Mean Difference: 0.67 (95% CI 0.23–1.11)
Sleep duration is not broadly associated with arterial stiffness across different ethnic groups, suggesting that the link between sleep duration and cardiovascular outcomes operates through other mechanisms.
No broad link between sleep duration and arterial stiffness; leaves open alternative mechanisms for sleep-CVD associations.
We examined the relationship between sleep duration and arterial stiffness among a multi-ethnic cohort, and whether the associations differed among ethnic minority groups in the Netherlands. Data were derived from 10 994 participants (aged 18-71 years) of the Healthy Life in an Urban Setting (HELIUS) study. Self-reported sleep duration was categorized into: short (<7 h/night), healthy (7-8 h/night) and long (≥9 h/night). Arterial stiffness was assessed by duplicate pulse-wave velocity (PWV in m/s) measurements using the Arteriograph system. The association of sleep duration with PWV was analysed using linear regression (β) with 95% confidence interval (CI). Results showed that neither short nor long sleep was related to PWV in all ethnic groups, except for long sleep in Dutch men which was associated with higher PWV (indicating stiffer arteries) after adjustment for potential confounders (β = 0.67, 95%CI, 0.23-1.11). Our study showed no convincing evidence that sleep duration was related to arterial stiffness among various ethnic groups. The link between sleep duration and cardiovascular outcomes does not seem to operate through arterial stiffness. Further research is needed to consolidate these findings.
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Anujuo et al. (2016) conducted a cohort in Arterial stiffness (n=10,994). Sleep duration (short <7 h/night, long ≥9 h/night) vs. Healthy sleep duration (7-8 h/night) was evaluated on Pulse-wave velocity (PWV in m/s) (β 0.67, 95% CI 0.23-1.11). Sleep duration was generally not associated with arterial stiffness, except for long sleep in Dutch men which was associated with higher pulse-wave velocity (β=0.67; 95% CI 0.23-1.11).
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