Key result
Erythrocyte hyperaggregability is linked to ~234% higher odds of metabolic syndrome.
Why the study?
Is metabolic syndrome associated with altered hemorheological parameters compared to controls without metabolic syndrome?
Population
150 individuals, comprising 61 patients with metabolic syndrome (MS) and 89 controls without MS.
Comparison
Metabolic syndrome (exposure) vs Controls without metabolic syndrome
Design
Case-control
Authors
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Should not yet inform metabolic syndrome management; hypothesis-generating for prospective cardiovascular outcome studies.
Case-Control (n=150)
Is metabolic syndrome associated with altered hemorheological parameters compared to controls without metabolic syndrome?
Odds Ratio: 3.34 (95% CI 1.4–7.93)
p-value: p=0.006
Metabolic syndrome is associated with an altered hemorheological profile, including increased blood and plasma viscosity, which may contribute to atherothrombotic events.
Vayá et al. (2011) conducted a case-control in Metabolic syndrome (n=150). Hemorheological alterations vs. Normal hemorheological profile was evaluated on Metabolic syndrome (OR 3.34, 95% CI 1.40-7.93, p=0.006). Erythrocyte hyperaggregability (OR 3.34; 95% CI 1.40-7.93; p=0.006) and hyperfibrinogenemia (OR 2.42; 95% CI 1.04-5.66; p=0.041) were independent predictors of metabolic syndrome.
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