Key result
Emergent Caesarean section and adrenalectomy completely resolve Cushing's syndrome-induced cardiomyopathy in a pregnant patient.
Why the study?
Congestive heart failure is rare during pregnancy, and this report highlights considering Cushing syndrome-induced cardiomyopathy as an underlying cause.
Case Report (n=1)
No
Cushing's syndrome-induced cardiomyopathy is a rare but reversible cause of congestive heart failure in pregnancy that can be successfully managed with delivery and adrenalectomy.
Congestive heart failure (CHF) is rare during pregnancy. We herein report a 35-year-old woman who developed CHF with severe left ventricular dysfunction at 35 weeks' gestation. She underwent emergency Caesarean section followed by intensive-care treatment for CHF. The diagnosis of Cushing's syndrome (CS) caused by adrenal adenoma was confirmed by endocrinological examinations and histology after adrenalectomy. She was discharged on heart failure medications and glucocorticoid replacement therapy. Both the symptoms and cardiac function had recovered after 12 months of follow-up. This case highlights the importance of considering CS-induced cardiomyopathy as a cause of CHF in pregnant women.
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Sakota et al. (2019) conducted a case report in Acute Congestive Heart Failure and Cushing's Syndrome-induced Cardiomyopathy in Pregnancy (n=1). Emergent Caesarean section followed by adrenalectomy was evaluated on Clinical and cardiac function recovery. Emergent Caesarean section followed by adrenalectomy led to the complete recovery of symptoms and cardiac function in a pregnant woman with Cushing's syndrome-induced cardiomyopathy.
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