Key result
The change ratio of arterial viscosity (%η) estimated via an oscillometric method successfully distinguished subjects at high risk of arteriosclerosis from healthy subjects with an area under the ROC curve of 0.786.
Why the study?
Does an algorithm estimating arterial viscosity using an oscillometric method accurately evaluate vascular endothelial function and distinguish healthy subjects from those at high risk of arteriosclerosis?
Cross-Sectional (n=43)
No
Does an algorithm estimating arterial viscosity using an oscillometric method accurately evaluate vascular endothelial function and distinguish healthy subjects from those at high risk of arteriosclerosis?
An oscillometric method for estimating arterial viscosity can evaluate vascular endothelial function and distinguish between healthy individuals and those at high risk of arteriosclerosis with moderate accuracy (AUC 0.77).
This paper proposes an algorithm for estimating the arterial viscosity using cuff pressures and pulse waves measured by an automatic oscillometric sphygmomanometer. A change in the arterial viscosity during the enclosed-zone flow-mediated dilation test is calculated as an index for evaluating the vascular endothelial function %η. In all, 43 individuals participated in this study. After the index %η was calculated, the accuracy of the index %η in distinguishing healthy subjects and subjects at a high risk of arteriosclerosis was tested via a receiving operating characteristic (ROC) analysis. The calculated %η for the healthy participants and those at a high risk of arteriosclerosis was 13.4 ± 55.1% and -32.7 ± 34.0% (mean ± S.D.), respectively. The area under the ROC curve was 0.77. Thus, it was concluded that the proposed method can be used to evaluate the vascular endothelial function.
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Tanaka et al. (2019) conducted a cross-sectional in Vascular endothelial dysfunction (n=43). High risk of arteriosclerosis vs. Healthy subjects was evaluated on Change ratio of arterial viscosity (%η) and its diagnostic accuracy (AUC) (AUC 0.786, p=0.006). The change ratio of arterial viscosity (%η) estimated via an oscillometric method successfully distinguished subjects at high risk of arteriosclerosis from healthy subjects with an area under the ROC curve of 0.786.
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