Key result
AGT gene core promoter variants show no association with hypertension.
Why the study?
Are core promoter variants of the AGT gene associated with hypertension in patients from Tamilnadu, India?
Case-Control (n=508)
Are core promoter variants of the AGT gene associated with hypertension in patients from Tamilnadu, India?
Core promoter variants of the AGT gene (A-20C, T-18C, G-6A) do not appear to be significantly associated with hypertension in the Tamilnadu population.
No takes yet. Share an insight, caveat, or question.
AGT promoter variants not linked to hypertension here; leaves open population-specific genetic contributions to blood pressure.
Rose et al. (2009) conducted a case-control in Hypertension (n=508). Core promoter variants (A-20C, T-18C and G-6A) of the Angiotensinogen (AGT) gene vs. Normotensive controls was evaluated on Hypertension. Core promoter variants (A-20C, T-18C and G-6A) of the Angiotensinogen (AGT) gene were not significantly associated with hypertension in patients from Tamilnadu, India.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: