Key result
Hypertension >10 years linked to ~25% lower myocardial hypertrophy prevalence but more pronounced LV wall hypertrophy.
Why the study?
Left ventricular remodeling and geometric changes determine cardiovascular mortality risk and precede heart failure, but patterns based on hypertension duration require clarification.
Does the duration of hypertension affect the pattern of left ventricular remodeling in hypertensive patients?
Observational (n=40)
No
Does the duration of hypertension affect the pattern of left ventricular remodeling in hypertensive patients?
Absolute Event Rate: 15% vs 20%
Long-term hypertension is associated with more pronounced left ventricular wall hypertrophy and concentric remodeling, highlighting the importance of early echocardiographic screening for risk stratification.
Longer hypertension duration may shape LV remodeling patterns; hypothesis-generating and should not yet change screening practice.
This article is devoted to the study of left ventricular remodeling processes in patients with different duration of hypertension history. The urgency of the problem lies in the fact that not only the increase in the mass of the left ventricle, but also the type of its geometric changes determines the risk of mortality of patients from cardiovascular complications. Cardiac remodeling precedes clinical manifestations of heart failure and accompanies them, as well as independently exacerbates the manifestations of diastolic and systolic ventricular dysfunction, is a serious independent prognostic risk factor for arrhythmias, coronary heart disease, strokes and sudden death. We conducted a retrospective analysis of 40 case histories of patients who were on inpatient treatment in GBUZ RM Republican hospital. Depending on the length of the disease, the subjects were divided into two groups: with the duration of the disease up to and more than 10 years. Echocardiography data were used to describe the nature of left ventricular remodeling. Our results showed that the prevalence of myocardial hypertrophy in patients with hypertension is low and is 20% in the group with anamnesis of GB<10 years and 15% — with anamnesis of GB>10 years. In the group of patients with long-term existing hypertension, more pronounced hypertrophy of the left ventricular walls is observed. In the long-term course of hypertension, the development of concentric remodeling and diastolic dysfunction of the left ventricle is an early marker of geometric restructuring of the left ventricle. Early detection of left ventricular remodeling processes is necessary for correct risk stratification and treatment tactics.
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Gorshenina et al. (2019) conducted an observational in Hypertension (n=40). Hypertension duration >10 years vs. Hypertension duration <10 years was evaluated on Prevalence of myocardial hypertrophy. A hypertension history of >10 years was associated with a 15% prevalence of myocardial hypertrophy compared to 20% in those with <10 years, alongside more pronounced left ventricular wall hypertrophy.
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