Key result
Heavy smoking linked to altered nocturnal blood pressure profiles in healthy normotensive subjects.
Why the study?
Does heavy smoking affect the nocturnal blood pressure profile in normotensive subjects?
Does heavy smoking affect the nocturnal blood pressure profile in normotensive subjects?
Heavy smoking for at least 20 years alters the physiological nocturnal blood pressure profile in otherwise healthy normotensive subjects.
Heavy smoking was associated with blunted nocturnal BP dipping in healthy normotensives; leaves open whether this predicts incident hypertension or events.
To the Editor.— The physiological nocturnal decline of the blood pressure in normotensive and hypertensive patients is not observed in autonomic dysfunction (eg, cardiac transplantation and some diabetic patients).1,2 The lack of the normal nocturnal decrease in blood pressure has also been found in a group of elderly hypertensive patients with cardiovascular damage and was attributed in this case to reduced arterial distensibility.3 We have shown, by studying a group of young subjects with no other risk factors and no atherosclerotic cardiovascular complications, that smoking affects the nocturnal blood pressure profile. Study.— We studied 22 normotensive subjects, heavy smokers for at least 20 years (12 men and 10 women, aged 36 to52 years; mean, 47 years) and 14 normotensive nonsmokers (eight men and six women, aged 38 to 54 years; mean, 50 years) by noninvasive 24-hour blood pressure monitoring, at 15-minute intervals. Blood pressure was assessed using
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Artom et al. (1991) conducted a letter in Normotension (n=36). Heavy smoking vs. Nonsmokers was evaluated on Nocturnal blood pressure profile. Heavy smoking affects the nocturnal blood pressure profile in normotensive subjects without other risk factors or atherosclerotic cardiovascular complications.
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