Key result
Sleep-induced baroreflex down-regulation may drive circulatory failure and progressive bradycardia in SIDS.
Population
Infants at risk of Sudden Infant Death Syndrome (SIDS)
Design
Review
Authors
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Hypothesis-generating for SIDS circulatory mechanisms; does not support changes to current sleep safety practices.
The authors hypothesize that SIDS is driven by a defect in circulatory control during sleep, leading to progressive bradycardia and hypoxia.
T. G. Matthews (2002) conducted a review in Sudden Infant Death Syndrome (SIDS). Sleep and SIDS risk factors (prone sleeping, overheating, co-sleeping) was evaluated. Sleep-induced down-regulation of the baroreceptor reflex, exacerbated by prone sleeping, overheating, and co-sleeping, may lead to circulatory failure and progressive bradycardia in SIDS.
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